Testosterone Isn't Just a Men's Hormone — Here's What It Does for Women

Testosterone plays a real role in women's energy, mood, muscle, and libido — but it's rarely discussed. Here's what the research actually shows.

8/25/20262 min read

Testosterone Isn't Just a Men's Hormone

If I say "testosterone therapy," most people picture a man in his 50s worried about his energy or his gym numbers. Almost no one pictures a 45-year-old woman who can't figure out why she's exhausted, foggy, and has completely lost interest in sex — even though her labs come back "normal."

That gap in the conversation isn't because the science isn't there. It's because testosterone in women has historically been under-discussed, under-tested, and under-treated.

Women make testosterone too. In fact, before menopause, women produce more testosterone than estrogen — it's just present at much lower levels than in men, and it plays a quieter but still important role: energy, mood, muscle mass, bone density, cognitive sharpness, and sexual function all have a testosterone component.

What low testosterone can look like. Fatigue that doesn't improve with sleep. Flat mood or low motivation. Difficulty building or keeping muscle despite consistent effort. Low libido or reduced sexual response. None of these are things most women think to connect to a single hormone — but in the right context, they can be.

The honest caveat. Testosterone therapy for women is not FDA-approved — there's currently no FDA-approved testosterone product made specifically for women in the U.S. That doesn't mean it isn't used or studied; it means it's prescribed off-label, based on the individual's symptoms, labs, and a risk-benefit conversation with their physician. That distinction matters, and any doctor discussing this with you should be upfront about it rather than glossing over it.

What the research shows so far. Studies have looked at testosterone's effects on sexual function, mood, bone density, muscle mass, and body composition in women, generally with encouraging results — though the research base is smaller and less mature than it is for estrogen and progesterone, and guidelines still vary across medical organizations. This is an area where good, individualized clinical judgment matters more than a one-size-fits-all protocol.

What this means for you: if you've been told your labs are "normal" but you don't feel like yourself, testosterone is worth asking about — not as a guaranteed fix, but as one piece of a much bigger hormonal picture that's often left out of the conversation entirely.

At ERAs, hormone evaluations always start with a full picture — energy, mood, sleep, strength, and labs — not just one number in isolation. Testosterone is one piece we look at for both men and women when the story calls for it.

Curious whether this applies to you? Book a visit and let's look at the whole picture together.

— Dr. Jennifer Hwang

Longevity, on your own terms.